Augmentation of interleukin-2 production and delayed hypersensitivity in mice infected with Mycobacterium bovis and fed a diet supplemented with vitamin A acetate

Infect Immun. 1985 May;48(2):581-3. doi: 10.1128/iai.48.2.581-583.1985.

Abstract

High-dose Mycobacterium bovis-infected mice fed a vitamin A acetate-supplemented diet developed a positive skin reaction to purified protein derivative of mycobacteria, and their spleen cells showed an increased IL-2 production in vitro.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Diterpenes
  • Female
  • Hypersensitivity, Delayed*
  • Interleukin-2 / biosynthesis*
  • Male
  • Mice
  • Mice, Inbred CBA
  • Mycobacterium bovis
  • Retinyl Esters
  • T-Lymphocytes / immunology
  • Tuberculosis / immunology*
  • Vitamin A / administration & dosage
  • Vitamin A / analogs & derivatives*
  • Vitamin A / pharmacology

Substances

  • Diterpenes
  • Interleukin-2
  • Retinyl Esters
  • Vitamin A
  • retinol acetate