Generation of an integration-free induced pluripotent stem cell (iPSC) line (SDHI001-A) from a 65-year old adult mitral valve prolapse (MVP) patient

Yiyao Zeng; Xin Tan; Shuai Xu; Kuangyi Wang; Xian Li; Yufeng Jiang

doi:10.1016/j.scr.2024.103464

Generation of an integration-free induced pluripotent stem cell (iPSC) line (SDHI001-A) from a 65-year old adult mitral valve prolapse (MVP) patient

Stem Cell Res. 2024 Aug:78:103464. doi: 10.1016/j.scr.2024.103464. Epub 2024 Jun 5.

Authors

Yiyao Zeng¹, Xin Tan¹, Shuai Xu¹, Kuangyi Wang¹, Xian Li¹, Yufeng Jiang²

Affiliations

¹ Department of Cardiology, The Fourth Hospital Affiliated to Soochow University, Medical Center of Soochow University, Suzhou Dushu Lake Hospital, No 9, Chongwen Road, Suzhou City 215000, China.
² Department of Cardiology, The Fourth Hospital Affiliated to Soochow University, Medical Center of Soochow University, Suzhou Dushu Lake Hospital, No 9, Chongwen Road, Suzhou City 215000, China. Electronic address: [email protected].

PMID: 38865834
DOI: 10.1016/j.scr.2024.103464

Abstract

Human iPSC line, SDHi001-A, was generated from 65-year-old male patient with mitral valve prolapse, using non-integrative reprogramming method. This cell line shows pluripotency both in vitro and in vivo, and has a normal karyotype.

Publication types

Case Reports

MeSH terms

Aged
Cell Differentiation
Cell Line
Humans
Induced Pluripotent Stem Cells* / metabolism
Male
Mitral Valve Prolapse* / pathology