Integration of Endogenous Opioid System Research in the Interprofessional Diagnosis and Treatment of Obesity and Eating Disorders

Marcela Rodriguez Flores; Sylvana Stephano Zuniga

doi:10.1007/978-3-031-45493-6_18

Integration of Endogenous Opioid System Research in the Interprofessional Diagnosis and Treatment of Obesity and Eating Disorders

Adv Neurobiol. 2024:35:357-380. doi: 10.1007/978-3-031-45493-6_18.

Authors

Marcela Rodriguez Flores¹, Sylvana Stephano Zuniga²

Affiliations

¹ Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK.
² Obesity and Eating Disorders Clinic, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Tlalpan, Mexico.

PMID: 38874732
DOI: 10.1007/978-3-031-45493-6_18

Abstract

This third and final chapter in our trilogy introduces the clinical distinctions and phenotypical similarities between obesity and eating disorders. Research elaborating on the shared neurobiological substrates for obesity and eating disorders is discussed. We present an interprofessional model of treatment for both disordered eating and for obesity. Additionally, this chapter establishes the translational importance of research connecting endogenous opioid activity with both obesity and eating disorders, with an emphasis on clinical interventions. We conclude with a discussion of future directions for research.

Keywords: Eating disorders; Endogenous opioids; Interprofessional treatment; Obesity.

MeSH terms

Feeding and Eating Disorders* / metabolism
Feeding and Eating Disorders* / therapy
Humans
Obesity* / diagnosis
Obesity* / metabolism
Obesity* / therapy
Opioid Peptides / metabolism

Substances

Opioid Peptides