Digital ischemic necrosis in a patient with systematic lupus erythematosus patient after severe acute respiratory syndrome coronavirus 2 infection: a case report

J Med Case Rep. 2024 Jun 19;18(1):295. doi: 10.1186/s13256-024-04567-3.

Abstract

Background: Patients with coronavirus disease 2019 have a high incidence of thrombosis that decreases after recovery. When coronavirus disease 2019 is accompanied by diseases prone to thrombosis, risk of post-infection thrombotic events may increase.

Case presentation: We report a case of digital ischemic gangrene in a 24-year-old Chinese female with systemic lupus erythematosus after recovery from coronavirus disease 2019. The pathogenesis was related to clinical characteristics of systemic lupus erythematosus, hypercoagulability caused by coronavirus disease 2019, and second-hit due to viral infection.

Conclusion: Patients with autoimmune diseases should remain alert to autoimmune system disorders induced by severe acute respiratory syndrome coronavirus 2 and other viruses. Treatment for these patients should be strictly standardized, and appropriate anticoagulation methods should be selected to prevent thrombosis.

Keywords: Arterial thromboembolism; COVID-19; Systemic lupus erythematosus; Thrombosis.

Publication types

  • Case Reports

MeSH terms

  • Anticoagulants / therapeutic use
  • COVID-19* / complications
  • Female
  • Fingers / blood supply
  • Fingers / pathology
  • Gangrene* / etiology
  • Humans
  • Ischemia* / etiology
  • Lupus Erythematosus, Systemic* / complications
  • Necrosis
  • SARS-CoV-2
  • Young Adult

Substances

  • Anticoagulants