Abstract
The authors review the advances of the last decade in bone marrow culture cytogenetics and immunology that have aided in understanding the pathophysiology of acute nonlymphocytic leukemia and they also discuss the major strides in treatment that have occurred.
MeSH terms
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Adolescent
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Adult
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Antigens, Surface / analysis
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Bone Marrow Transplantation
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Child
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Child, Preschool
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Chromosome Aberrations
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Cytarabine / administration & dosage
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Doxorubicin / administration & dosage
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Hematopoietic Stem Cells / ultrastructure
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Humans
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Leukemia / genetics
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Leukemia / pathology
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Leukemia / therapy*
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Leukemia, Myeloid, Acute / therapy
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Nervous System Neoplasms / prevention & control
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Prednisolone / administration & dosage
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Prognosis
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Recurrence
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Risk
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Vincristine / administration & dosage
Substances
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Antigens, Surface
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Cytarabine
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Vincristine
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Doxorubicin
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Prednisolone