Bacterial vaginosis in pregnant women: A comparison of the Nugent Score with a multiplex PCR

Tom Theiler; Sarah Schoeler; Mareike Möllers; Franziska Schuler; Ioana D Olaru; Frieder Schaumburg

doi:10.1016/j.diagmicrobio.2024.116403

Bacterial vaginosis in pregnant women: A comparison of the Nugent Score with a multiplex PCR

Diagn Microbiol Infect Dis. 2024 Sep;110(1):116403. doi: 10.1016/j.diagmicrobio.2024.116403. Epub 2024 Jun 13.

Authors

Tom Theiler¹, Sarah Schoeler², Mareike Möllers³, Franziska Schuler², Ioana D Olaru², Frieder Schaumburg²

Affiliations

¹ Institute of Medical Microbiology, University Hospital Münster, Münster, Germany. Electronic address: [email protected].
² Institute of Medical Microbiology, University Hospital Münster, Münster, Germany.
³ Department of Obstetrics and Gynecology, University Hospital Münster, Münster, Germany.

PMID: 38908040
DOI: 10.1016/j.diagmicrobio.2024.116403

Abstract

We evaluated the Nugent score against a multiplex real-time PCR (reference) for diagnosing bacterial vaginosis (BV) in 140 pregnant women. The Nugent score had a sensitivity of 60 %, a specificity of 81 % and a negative predictive value of 92 % - therefore a tool to rule out BV in pregnant women.

Keywords: Bacterial Vaginosis; Nugent score; Polymerase Chain Reaction; Vaginal Diseases; Vaginal Health; pregnancy.

Publication types

Comparative Study
Evaluation Study

MeSH terms

Adult
Female
Humans
Multiplex Polymerase Chain Reaction* / methods
Predictive Value of Tests
Pregnancy
Pregnancy Complications, Infectious* / diagnosis
Pregnancy Complications, Infectious* / microbiology
Sensitivity and Specificity*
Vaginosis, Bacterial* / diagnosis
Vaginosis, Bacterial* / microbiology
Young Adult