Sodium Dehydroacetate and Dehydroacetic Acid

Int J Toxicol. 2024 Oct;43(4_suppl):130-134. doi: 10.1177/10915818241260276. Epub 2024 Jun 24.

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) first published a safety assessment of Sodium Dehydroacetate and Dehydroacetic Acid in 1985. The Panel previously concluded that Sodium Dehydroacetate and Dehydroacetic Acid are safe as used in the present practices of use and concentration, as stated in that report. Upon re-review in 2003, the Panel reaffirmed the original conclusion, as published in 2006. The Panel reviewed updated frequency and concentration of use data again in 2023, in addition to any newly available, relevant safety data. Considering this information, as well as the information provided in the original safety assessment and the prior re-review document, the Panel reaffirmed the 1985 conclusion.

Keywords: Cosmetic Ingredient Review; Cosmetics; Expert Panel for Cosmetic Ingredient Safety; Ingredients; Safety; Sodium Dehydroacetate.

Publication types

  • Review

MeSH terms

  • Animals
  • Consumer Product Safety
  • Cosmetics* / chemistry
  • Cosmetics* / pharmacokinetics
  • Cosmetics* / toxicity
  • Humans
  • Pyrones
  • Risk Assessment
  • Toxicity Tests

Substances

  • dehydroacetic acid
  • Cosmetics
  • Pyrones