Glutamic acid decarboxylase-containing axons synapse on LHRH neurons in the rat medial preoptic area

Neuroendocrinology. 1985 Jun;40(6):536-9. doi: 10.1159/000124127.

Abstract

A double-label electron microscopic immunostaining procedure was employed to examine the interconnections of glutamic acid decarboxylase(GAD)- and LHRH-immunoreactive neurons in the medial preoptic area of the rat. The results provide ultrastructural evidence that GABA-ergic neurons establish symmetric (Gray II) synapses on LHRH neurons.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Axons / analysis
  • Axons / ultrastructure*
  • Female
  • Glutamate Decarboxylase / analysis*
  • Gonadotropin-Releasing Hormone / analysis*
  • Immunologic Techniques
  • Microscopy, Electron
  • Neurons / analysis
  • Neurons / ultrastructure*
  • Preoptic Area / ultrastructure*
  • Rats
  • Rats, Inbred Strains
  • Synapses / ultrastructure

Substances

  • Gonadotropin-Releasing Hormone
  • Glutamate Decarboxylase