Immunological illnesses related to wheat represent an epidemiologically relevant phenomenon at a pediatric age. The term "Wheat-related disorders" involves a spectrum of diseases: celiac disease, IgE-mediated wheat allergy, non-IgE mediated wheat allergy, wheat-related eosinophilic esophagitis, and non-celiac gluten sensitivity. Their pathogenesis is different. At the same time, wheat represents their common point. This article aims to the state-of-the-art and new clinical evidence in pediatric age.
Keywords: IgE-mediated wheat allergy; celiac disease; non-IgE mediated wheat allergy; non-celiac gluten sensitivity; wheat-related disorders; wheat-related eosinophilic esophagitis.