Deep Learning in Neovascular Age-Related Macular Degeneration

Medicina (Kaunas). 2024 Jun 17;60(6):990. doi: 10.3390/medicina60060990.

Abstract

Background and objectives: Age-related macular degeneration (AMD) is a complex and multifactorial condition that can lead to permanent vision loss once it progresses to the neovascular exudative stage. This review aims to summarize the use of deep learning in neovascular AMD. Materials and Methods: Pubmed search. Results: Deep learning has demonstrated effectiveness in analyzing structural OCT images in patients with neovascular AMD. This review outlines the role of deep learning in identifying and measuring biomarkers linked to an elevated risk of transitioning to the neovascular form of AMD. Additionally, deep learning techniques can quantify critical OCT features associated with neovascular AMD, which have prognostic implications for these patients. Incorporating deep learning into the assessment of neovascular AMD eyes holds promise for enhancing clinical management strategies for affected individuals. Conclusion: Several studies have demonstrated effectiveness of deep learning in assessing neovascular AMD patients and this has a promising role in the assessment of these patients.

Keywords: age-related macular degeneration; artificial intelligence; biomarker; deep learning; neovascular age-related macular degeneration; neovascularization; optical coherence tomography.

Publication types

  • Review

MeSH terms

  • Deep Learning*
  • Humans
  • Macular Degeneration*
  • Tomography, Optical Coherence* / methods

Grants and funding

This research received no external funding.