Central Myoepithelioma of the Maxilla

Head Neck Pathol. 2024 Jun 28;18(1):61. doi: 10.1007/s12105-024-01665-y.

Abstract

Myoepithelioma is a benign salivary gland tumor. Central myoepitheliomas are very rare. The aim of this report was to describe a case of maxillary myoepithelioma. A 14-year-old female patient presented with an multilocular lesion in the anterior maxilla, with nearly 8 months of duration. The lesion was asymptomatic, and the patient's dental history was unremarkable. The diagnostic hypothesis was an odontogenic tumor. Biopsy specimen consisted of nests of plasmacytoid cells in a myxoid stroma without duct formation. No cellular atypia or bone and cartilage formation were noted. The neoplastic cells were positive for Pan-cytokeratin, S100, CK7, and CK8. The final diagnosis was myoepithelioma. The patient was treated by surgical excision followed by bone curettage, and no signs of recurrence were found after 8 years of treatment.

Keywords: Bone; Jaw; Maxilla; Myoepithelioma.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Biomarkers, Tumor / analysis
  • Female
  • Humans
  • Maxillary Neoplasms* / pathology
  • Maxillary Neoplasms* / surgery
  • Myoepithelioma* / pathology

Substances

  • Biomarkers, Tumor