Performance of a rapid recency assay for detection of early HIV infection

J Clin Virol. 2024 Oct:174:105708. doi: 10.1016/j.jcv.2024.105708. Epub 2024 Jun 22.

Abstract

The Asanté HIV-1 Rapid Recency assay's 'verification' line detected HIV infection a median of 18 days later than a nucleic acid detection assay and performed similarly to 19 other existing rapid HIV antibody tests. Pending regulatory approval, the assay could be an option with other rapid tests in national HIV-1 testing algorithms, which would allow collection of HIV recency data as part of a national screening program without requiring additional testing.

Keywords: Early infection; HIV; HIV antibody; Recency testing.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Early Diagnosis
  • Female
  • HIV Antibodies / blood
  • HIV Infections* / diagnosis
  • HIV Testing / methods
  • HIV-1* / genetics
  • HIV-1* / immunology
  • HIV-1* / isolation & purification
  • Humans
  • Male
  • Middle Aged
  • Molecular Diagnostic Techniques / methods
  • Molecular Diagnostic Techniques / standards
  • Nucleic Acid Amplification Techniques / methods
  • Reagent Kits, Diagnostic / standards
  • Sensitivity and Specificity
  • Time Factors

Substances

  • HIV Antibodies
  • Reagent Kits, Diagnostic