In adults with COVID-19 and severe hypoxemia, lower vs. higher oxygenation targets increased days alive without life support

Daniel A Sweeney; Andre C Kalil

doi:10.7326/ANNALS-24-00558-JC

In adults with COVID-19 and severe hypoxemia, lower vs. higher oxygenation targets increased days alive without life support

Ann Intern Med. 2024 Jul;177(7):JC77. doi: 10.7326/ANNALS-24-00558-JC. Epub 2024 Jul 2.

Authors

Daniel A Sweeney¹, Andre C Kalil²

Affiliations

¹ University of California San Diego <<Beth: There is no comma between California and San Diego on the institution web site. I think this is the institution name. Jean>>, La Jolla, California, USA (D.A.S.).
² University of Nebraska Medical Center, Omaha, Nebraska, USA (A.C.K.).

PMID: 38950395
DOI: 10.7326/ANNALS-24-00558-JC

Abstract

Nielsen FM, Klitgaard TL, Siegemund M, et al; HOT-COVID Trial Group. Lower vs higher oxygenation target and days alive without life support in COVID-19: the HOT-COVID randomized clinical trial. JAMA. 2024;331:1185-1194. 38501214.

Publication types

Comment

MeSH terms

Adult
COVID-19* / complications
Female
Humans
Hypoxia*
Life Support Care
Male
Middle Aged
Oxygen / blood
Oxygen / therapeutic use
Oxygen Inhalation Therapy
SARS-CoV-2*

Substances

Oxygen