Managing abdominal cocoon syndrome complicated by intestinal necrosis and unexpected amelioration of depression after surgery: a case report

J Med Case Rep. 2024 Jul 6;18(1):322. doi: 10.1186/s13256-024-04650-9.

Abstract

Background: Abdominal cocoon is a very uncommon yet dangerous cause of intestinal obstruction.

Case presentation: We present a case of a 62-year-old Asian male patient with a history of depression who exhibited an idiopathic abdominal cocoon complicated by necrosis. Upon laparotomy investigation, nearly the entire small intestine was enveloped in a thick membrane resembling a cocoon, and it was discovered that he lacked a greater omentum. The patient recovered well and was discharged on an oral diet on the 20th day following surgery. During the 3-month follow-up, the patient was asymptomatic, even gaining 10 kg in weight, and noted that his depression had improved.

Conclusions: Small bowel obstruction presents with nonspecific symptoms, posing challenges in differential diagnosis. Contrast-enhanced computed tomography is recommended since it facilitates precise preoperative assessment, optimizing surgical planning and reducing postoperative complications. Remarkably, cessation of antidepressant medication post-surgery hints at a potential correlation between omental deficit, gut microbiota alterations, and depressive symptoms.

Keywords: Abdominal cocoon; Case report; Depression; Encapsulating sclerosing peritonitis; Small bowel obstruction.

Publication types

  • Case Reports

MeSH terms

  • Antidepressive Agents / therapeutic use
  • Depression / etiology
  • Humans
  • Intestinal Obstruction* / etiology
  • Intestinal Obstruction* / surgery
  • Intestine, Small
  • Male
  • Middle Aged
  • Necrosis*
  • Postoperative Complications
  • Syndrome
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Antidepressive Agents