Renal Artery Denervation for the Management of Hypertension: Current Trends and Future Direction

Am J Med. 2024 Dec;137(12):1190-1199.e4. doi: 10.1016/j.amjmed.2024.06.029. Epub 2024 Jul 7.

Abstract

Renal artery denervation has re-emerged as a potential therapeutic option for patients with hypertension, especially those resistant to conventional pharmacotherapy. This comprehensive review explores the importance of careful patient selection, procedural techniques, clinical efficacy, safety considerations, and future directions of renal artery denervation in hypertension management. Drawing upon a wide range of available evidence, this review aims to provide a thorough understanding of the procedure and its role in contemporary hypertension treatment paradigms.

Keywords: Blood pressure; Hypertension; Interventional cardiology; Renal artery denervation; Review article; Sympathetic nervous system.

Publication types

  • Review

MeSH terms

  • Catheter Ablation / methods
  • Catheter Ablation / trends
  • Denervation / methods
  • Humans
  • Hypertension* / surgery
  • Patient Selection
  • Renal Artery* / innervation
  • Renal Artery* / surgery
  • Sympathectomy* / methods
  • Sympathectomy* / trends