Case Report: Chronic pancreatitis in children as the cumulative effect of bilio-pancreatic abnormalities and genetic mutations

Front Pediatr. 2024 Jun 21:12:1393891. doi: 10.3389/fped.2024.1393891. eCollection 2024.

Abstract

Pancreatitis, in general, is a high-morbidity condition. Genetic conditions and anatomic variants are sometimes seen, especially in children, where biliary etiologies and alcohol are less common than in adults. The decision to intervene, the combined operative-endoscopic strategy, and the timing pose unique challenges. We report the case of a 10-year-old boy with PRSS1 mutation and pancreatic duct duplication, discussing the management and reviewing the recent reports in the Literature.

Keywords: PRSS1; anatomic variants; bilio-pancreatic malformation; children; chronic pancreatitis; endoscopy; genetic malformations; pancreatic duct duplication.

Publication types

  • Case Reports

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article.