Co-occurrence of mycotoxins in stored maize from southern and southwestern Ethiopia

Food Addit Contam Part B Surveill. 2024 Sep;17(3):261-274. doi: 10.1080/19393210.2024.2372426. Epub 2024 Jul 9.

Abstract

Maize grain samples collected from 129 small-scale farmers' stores in southern and southwestern Ethiopia were analysed by LC-MS/MS for a total of 218 mycotoxins and other fungal metabolites of which 15% were regulated mycotoxins. Mycotoxins produced by Penicillium, Aspergillus, and Fusarium accounted for 31%, 17%, and 12% of the metabolites, respectively. Most of the current samples were contaminated by masked and/or emerging mycotoxins with moniliformin being the most prevalent one, contaminating 93% of the samples. Each sample was co-contaminated by 3 to 114 mycotoxins/fungal metabolites. Zearalenone, fumonisin B1, and deoxynivalenol were the dominant mycotoxins, occurring in 78%, 61%, and 55% of the samples with mean concentrations of 243, 429, and 530 µg/kg, respectively. The widespread co-occurrence of several mycotoxins in the samples may pose serious health risks due to synergistic/additional effects.

Keywords: Ethiopia; LC-MS/MS; maize; metabolites; toxigenic fungi.

MeSH terms

  • Aspergillus
  • Chromatography, Liquid / methods
  • Cyclobutanes
  • Ethiopia
  • Food Contamination* / analysis
  • Food Storage
  • Fumonisins* / analysis
  • Fusarium / chemistry
  • Fusarium / metabolism
  • Humans
  • Mycotoxins* / analysis
  • Penicillium
  • Tandem Mass Spectrometry*
  • Trichothecenes / analysis
  • Zea mays* / chemistry
  • Zea mays* / microbiology
  • Zearalenone / analysis

Substances

  • Mycotoxins
  • Fumonisins
  • Zearalenone
  • fumonisin B1
  • Trichothecenes
  • deoxynivalenol
  • moniliformin
  • Cyclobutanes