Incidental seminoma in nonobstructive azoospermia: a case report

F S Rep. 2024 Apr 15;5(2):211-213. doi: 10.1016/j.xfre.2024.04.001. eCollection 2024 Jun.

Abstract

Objective: To report on the incidental finding of invasive seminoma in a patient with nonobstructive azoospermia during microdissection testicular sperm extraction.

Design: Case report.

Patients: A single patient diagnosed with nonobstructive azoospermia underwent microdissection testicular sperm extraction, and an incidental finding of invasive seminoma was made upon histopathological analysis.

Results: An incidental discovery of invasive seminoma was observed in the sample pathology obtained during the microdissection testicular sperm extraction. Consequently, the patient underwent further diagnostic workup and a radical orchiectomy.

Conclusions: Men with male factor infertility are at increased risk of testicular cancer. As such, it is imperative to incorporate a thorough physical examination and relevant imaging into their diagnostic process. Additionally, it is advisable to include histopathological analysis for all individuals undergoing microdissection testicular sperm extraction.

Keywords: Nonobstructive azoospermia; case report; male factor infertility; microdissection testicular sperm extraction; seminoma.