Use of hiPSC-derived cardiomyocytes to study LQTS-variant specific proarrhythmic effects of drugs

Vascul Pharmacol. 2024 Jun:155:107347. doi: 10.1016/j.vph.2024.107347.
No abstract available

MeSH terms

  • Action Potentials* / drug effects
  • Heart Rate / drug effects
  • Humans
  • Induced Pluripotent Stem Cells* / drug effects
  • Induced Pluripotent Stem Cells* / metabolism
  • Long QT Syndrome* / chemically induced
  • Long QT Syndrome* / physiopathology
  • Myocytes, Cardiac* / drug effects
  • Myocytes, Cardiac* / metabolism
  • Myocytes, Cardiac* / pathology
  • Pharmacogenomic Variants
  • Phenotype