Abstract
Fifty women were randomly given one, two, or three 2 gm parenteral doses of cefoxitin with placebo blinding perioperatively at abdominal hysterectomy. A single preoperative intramuscular dose was more efficient, less frequently associated with the development of bacterial resistance, and less expensive than two or three doses.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Bacterial Infections / prevention & control*
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Cefoxitin / therapeutic use*
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Clinical Trials as Topic
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Double-Blind Method
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Drug Resistance, Microbial
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Female
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Humans
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Hysterectomy / methods*
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Postoperative Complications / prevention & control
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Premedication*