Elevated DKK1 expression: a promising prognostic biomarker and therapeutic target in head and neck squamous cell carcinoma

Expert Rev Anticancer Ther. 2024 Sep;24(9):917-919. doi: 10.1080/14737140.2024.2379920. Epub 2024 Jul 15.
No abstract available

Keywords: Dickkopf-1 (DKK1); head and neck squamous cell carcinoma (HNSCC); personalized treatment; prognostic biomarker; radiotherapy resistance.

Publication types

  • Editorial

MeSH terms

  • Biomarkers, Tumor* / genetics
  • Biomarkers, Tumor* / metabolism
  • Gene Expression Regulation, Neoplastic
  • Head and Neck Neoplasms* / genetics
  • Head and Neck Neoplasms* / metabolism
  • Head and Neck Neoplasms* / pathology
  • Head and Neck Neoplasms* / therapy
  • Humans
  • Intercellular Signaling Peptides and Proteins* / metabolism
  • Molecular Targeted Therapy*
  • Prognosis
  • Squamous Cell Carcinoma of Head and Neck* / genetics
  • Squamous Cell Carcinoma of Head and Neck* / metabolism
  • Squamous Cell Carcinoma of Head and Neck* / pathology

Substances

  • Biomarkers, Tumor
  • Intercellular Signaling Peptides and Proteins
  • DKK1 protein, human