The comprehensive review on 3D printing- pharmaceutical drug delivery and personalized food and nutrition

Food Chem. 2024 Nov 30:459:140348. doi: 10.1016/j.foodchem.2024.140348. Epub 2024 Jul 5.

Abstract

Three-dimensional printing is one of the emerging technologies that is gaining interest from the pharmaceutical industry as it provides an opportunity to customize drugs according to each patient's needs. Combining different active pharmaceutical ingredients, using different geometries, and providing sustained release enhances the effectiveness of medicine. One of the most innovative uses of 3D printing is producing fabrics, medical devices, medical implants, orthoses, and prostheses. This review summarizes the various 3D printing techniques such as stereolithography, inkjet printing, thermal inkjet printing, fused deposition modelling, extrusion printing, semi-solid extrusion printing, selective laser sintering, and hot-melt extrusion. Also, discusses the drug relies profile and its mechanisms, characteristics, and applications of the most common types of 3D printed API formulations and its recent development. Here, Authors also, summarizes the central flow of 3D food printing process and knowledge extension toward personalized nutrition.

Keywords: 3D printing; Drug delivery; FDM; Pharma foods; Tablet-in-device.

Publication types

  • Review

MeSH terms

  • Drug Delivery Systems* / instrumentation
  • Humans
  • Pharmaceutical Preparations / chemistry
  • Precision Medicine*
  • Printing, Three-Dimensional*

Substances

  • Pharmaceutical Preparations