Nanoparticles in cancer theragnostic and drug delivery: A comprehensive review

Life Sci. 2024 Sep 1:352:122899. doi: 10.1016/j.lfs.2024.122899. Epub 2024 Jul 9.

Abstract

This comprehensive review provides an in-depth analysis of how nanotechnology has revolutionized cancer theragnostic, which combines diagnostic and therapeutic methods to customize cancer treatment. The study examines the unique attributes, uses, and difficulties linked to different types of nanoparticles, including gold, iron oxide, silica, Quantum dots, Carbon nanotubes, and liposomes, in the context of cancer treatment. In addition, the paper examines the progression of nanotheranostics, emphasizing its uses in precise medication administration, photothermal therapy, and sophisticated diagnostic methods such as MRI, CT, and fluorescence imaging. Moreover, the article highlights the capacity of nanoparticles to improve the effectiveness of drugs, reduce the overall toxicity in the body, and open up new possibilities for treating cancer by releasing drugs in a controlled manner and targeting specific areas. Furthermore, it tackles concerns regarding the compatibility of nanoparticles and their potential harmful effects, emphasizing the significance of continuous study to improve nanotherapeutic methods for use in medical treatments. The review finishes by outlining potential future applications of nanotechnology in predictive oncology and customized medicine.

Keywords: Cancer cells; Diagnostic modalities; Drug delivery; Nanoparticles; Therapeutic functions.

Publication types

  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / therapeutic use
  • Drug Delivery Systems* / methods
  • Humans
  • Nanoparticles*
  • Nanotechnology / methods
  • Neoplasms* / drug therapy
  • Theranostic Nanomedicine / methods

Substances

  • Antineoplastic Agents