The merger of two major families of proteins that regulate cellular processes

Karlett J Parra

doi:10.1016/j.str.2024.06.008

The merger of two major families of proteins that regulate cellular processes

Structure. 2024 Jul 11;32(7):851-853. doi: 10.1016/j.str.2024.06.008.

Author

Karlett J Parra¹

Affiliation

¹ Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, NM, USA. Electronic address: [email protected].

PMID: 38996510
DOI: 10.1016/j.str.2024.06.008

Abstract

In this issue of Structure, Oot and Wilkens¹ present new mechanistic insights to finally merge the function of V-ATPase and TLDc domain proteins. They show that TLDc proteins directly affect V-ATPase activity and assembly, expanding our understanding of how V-ATPase and TLDc proteins exert a plethora of biological functions.

MeSH terms

Humans
Protein Domains
Vacuolar Proton-Translocating ATPases* / chemistry
Vacuolar Proton-Translocating ATPases* / metabolism

Substances

Vacuolar Proton-Translocating ATPases