Post-Acute Sequelae of SARS-CoV-2 Infection and Its Impact on Adolescents and Young Adults

Camille A Broussard; Alba Azola; Peter C Rowe

doi:10.1016/j.pcl.2024.04.004

Post-Acute Sequelae of SARS-CoV-2 Infection and Its Impact on Adolescents and Young Adults

Pediatr Clin North Am. 2024 Aug;71(4):613-630. doi: 10.1016/j.pcl.2024.04.004. Epub 2024 May 8.

Authors

Camille A Broussard¹, Alba Azola², Peter C Rowe³

Affiliations

¹ Department of Pediatrics, Division of Adolescent & Young Adult Medicine, Johns Hopkins School of Medicine, 200 North Wolfe Street Room 2067, Baltimore, MD 21287, USA. Electronic address: [email protected].
² Department of Pediatrics, Division of Adolescent & Young Adult Medicine, Johns Hopkins School of Medicine, 200 North Wolfe Street Room 2069, Baltimore, MD 21287, USA; Department of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine, 200 North Wolfe Street Room 2069, Baltimore, MD 21287, USA.
³ Department of Pediatrics, Division of Adolescent & Young Adult Medicine, Johns Hopkins School of Medicine, 200 North Wolfe Street Room 2077, Baltimore, MD 21287, USA.

PMID: 39003005
DOI: 10.1016/j.pcl.2024.04.004

Abstract

This review discusses the varying definitions for post-acute sequelae of SARS CoV-2 infection (PASC) in adolescents and young adults (AYAs), symptom profiles of AYAs with PASC, and assessment and management strategies when AYAs present with symptoms concerning for PASC. Additionally, it reviews the impact that PASC can have on AYAs and includes strategies for providers to support AYAs with PASC. Finally, it concludes with a discussion around equity in the care of AYAs with possible PASC.

Keywords: Adolescent; Chronic fatigue syndrome; Long COVID; Myalgic encephalomyelitis; Orthostatic intolerance; Post-COVID-19 condition; Post-acute sequelae of SARS CoV-2 infection.

Publication types

Review

MeSH terms

Adolescent
COVID-19* / complications
COVID-19* / epidemiology
Humans
Post-Acute COVID-19 Syndrome*
SARS-CoV-2
Young Adult