A multi-epigenomic map of endurance exercise training

Trends Genet. 2024 Sep;40(9):736-738. doi: 10.1016/j.tig.2024.06.005. Epub 2024 Jul 12.

Abstract

The Molecular Transducers of Physical Activity Consortium (MoTrPAC) aims to comprehensively map molecular alterations in response to acute exercise and chronic training. In one of a recent series of papers from MoTrPAC, Nair et al. provide the first multi-epigenomic and transcriptomic integration across eight tissues in both sexes following adaptation to endurance exercise training (EET).

Keywords: endurance training; epigenetics; exercise; skeletal muscle; transcriptomics; ‘omics.

MeSH terms

  • Endurance Training*
  • Epigenesis, Genetic
  • Exercise*
  • Female
  • Humans
  • Male
  • Physical Endurance / genetics
  • Transcriptome / genetics