The difference in core-surface temperature indicates the prognosis of heart failure patients

Biomark Med. 2024;18(9):441-448. doi: 10.1080/17520363.2024.2342233. Epub 2024 May 24.

Abstract

Aim: To evaluate the difference between core temperature and surface temperature (ΔT) as an index for the prognosis of heart failure (HF). Patients & methods: Core temperature and surface temperature were measured in 253 patients with HF. The association of ΔT with prognostic indicators of HF was analyzed. Results: Patients with ΔT ≥2°C were more likely to have lower left ventricular ejection fraction and lower estimated glomerular filtration rate, higher levels of troponin T, brain natriuretic peptide and procalcitonin, and high blood urea nitrogen/creatinine ratio. The risk of death increased by 32% for a 1°C increase in ΔT and was 4.36-times higher in the ΔT ≥2°C group than in the ΔT <2°C group. Conclusion: ΔT may be used to predict the prognosis of patients with HF.

Keywords: core temperature; heart failure; mortality; prognosis; surface temperature.

Plain language summary

[Box: see text].

MeSH terms

  • Aged
  • Aged, 80 and over
  • Blood Urea Nitrogen
  • Body Temperature
  • Creatinine / blood
  • Female
  • Glomerular Filtration Rate
  • Heart Failure* / blood
  • Heart Failure* / diagnosis
  • Heart Failure* / mortality
  • Heart Failure* / physiopathology
  • Humans
  • Male
  • Middle Aged
  • Natriuretic Peptide, Brain / blood
  • Procalcitonin / blood
  • Prognosis
  • Stroke Volume
  • Troponin T / blood

Substances

  • Troponin T
  • Natriuretic Peptide, Brain
  • Creatinine
  • Procalcitonin