Identification of the new allele HLA-C*04:01:01:186 in a Greek individual using next generation sequencing

HLA. 2024 Jul;104(1):e15569. doi: 10.1111/tan.15569.

Abstract

The newly discovered HLA-C*04:01:01:186 allele differs from HLA-C*04:01:01:01 by a single nucleotide substitution in intron 3.

Keywords: HLA‐C*04:01:01:186 novel allele; HLA‐genotyping; Illumina; next generation sequencing.

Publication types

  • Letter

MeSH terms

  • Alleles*
  • Base Sequence
  • Exons
  • Greece
  • HLA-C Antigens* / genetics
  • High-Throughput Nucleotide Sequencing* / methods
  • Histocompatibility Testing* / methods
  • Humans
  • Introns*
  • Polymorphism, Single Nucleotide
  • Sequence Analysis, DNA / methods

Substances

  • HLA-C Antigens
  • HLA-C*04 antigen