Role of microRNAs in immune regulation and pathogenesis of Chlamydia trachomatis and Chlamydia muridarum infections: a rapid review

Microbes Infect. 2024 Nov-Dec;26(8):105397. doi: 10.1016/j.micinf.2024.105397. Epub 2024 Jul 17.

Abstract

MicroRNAs in Chlamydia trachomatis (CT) and Chlamydia muridarum (CM) infections are an emerging topic of research that provide knowledge that could advance vaccine development and strategies for managing infection. This rapid review summarizes human and murine studies on miRNA expression in CT and CM infections in vivo and ex vivo.

Keywords: Biomarker; Chlamydia; Expression; Immune; miRNA; microRNA.

Publication types

  • Review

MeSH terms

  • Animals
  • Chlamydia Infections* / immunology
  • Chlamydia Infections* / microbiology
  • Chlamydia muridarum* / genetics
  • Chlamydia muridarum* / immunology
  • Chlamydia trachomatis* / genetics
  • Chlamydia trachomatis* / immunology
  • Chlamydia trachomatis* / pathogenicity
  • Host-Pathogen Interactions / genetics
  • Host-Pathogen Interactions / immunology
  • Humans
  • Mice
  • MicroRNAs* / genetics

Substances

  • MicroRNAs