Pure red cell aplasia secondary to erythropoietin therapy

Clin Med (Lond). 2024 Jul;24(4):100229. doi: 10.1016/j.clinme.2024.100229. Epub 2024 Jul 17.

Abstract

We report a case series of two patients with chronic kidney disease (CKD) who developed erythropoietin-induced pure red cell aplasia following a change in erythropoietin preparation. Both patients responded well to immunosuppressive treatments, but unfortunately developed severe infections as a result of being immunosuppressed.

Keywords: Erythropoietin; Pure red cell aplasia.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Erythropoietin* / adverse effects
  • Erythropoietin* / therapeutic use
  • Female
  • Hematinics / adverse effects
  • Hematinics / therapeutic use
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use
  • Kidney Failure, Chronic
  • Male
  • Middle Aged
  • Recombinant Proteins / adverse effects
  • Recombinant Proteins / therapeutic use
  • Red-Cell Aplasia, Pure* / chemically induced

Substances

  • Erythropoietin
  • Immunosuppressive Agents
  • Hematinics
  • Recombinant Proteins