Lingual neoplasia in nonhuman primates: Description of five cases and a literature review

J Med Primatol. 2024 Aug;53(4):e12725. doi: 10.1111/jmp.12725.

Abstract

Background: Documentation of lingual tumors is scarce in nonhuman primates.

Methods: Through a multi-institutional retrospective study we compile cases of primary and metastatic neoplasia in non-human primates.

Results: We describe five cases of lingual neoplasia. Three cases are primary lingual tumors: chondro-osteoblastic lipoma in a howler monkey, squamous cell carcinoma, and fibroma in two baboons. We describe two cases of metastatic lymphoma in the tongue in rhesus macaques. A literature review of published lingual neoplasia in nonhuman primates is included in this manuscript.

Conclusion: Lingual neoplasia is seldom reported in non-human primates.

Keywords: Alouatta palliata; Macaca mulatta; Papio spp.; chondro‐osteoblastic lipoma; fibroma; lymphoma; squamous cell carcinoma; tongue.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Animals
  • Carcinoma, Squamous Cell / diagnosis
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / veterinary
  • Female
  • Lipoma / diagnosis
  • Lipoma / pathology
  • Lipoma / veterinary
  • Macaca mulatta
  • Male
  • Monkey Diseases* / diagnosis
  • Monkey Diseases* / pathology
  • Papio*
  • Retrospective Studies
  • Tongue Neoplasms* / diagnosis
  • Tongue Neoplasms* / pathology
  • Tongue Neoplasms* / veterinary