Crimean-Congo Hemorrhagic Fever Virus Kinetics in Serum, Saliva, and Urine, Iran, 2018

Emerg Infect Dis. 2024 Aug;30(8):1706-1709. doi: 10.3201/eid3008.240036.

Abstract

Little is known about using noninvasive samples for diagnosing Crimean-Congo hemorrhagic fever (CCHF). We investigated detection of CCHF virus in serum, saliva, and urine samples. Our results indicate that serum is the best sample type for CCHF diagnosis; saliva can be used for noninvasive sampling.

Keywords: Crimean-Congo hemorrhagic fever; Iran; arboviruses; emerging infectious diseases; laboratory diagnosis; vector-borne infections; viral hemorrhagic fevers; viral kinetics; viruses; zoonoses.

MeSH terms

  • Adult
  • Female
  • Hemorrhagic Fever Virus, Crimean-Congo* / isolation & purification
  • Hemorrhagic Fever, Crimean* / diagnosis
  • Hemorrhagic Fever, Crimean* / epidemiology
  • Hemorrhagic Fever, Crimean* / urine
  • Hemorrhagic Fever, Crimean* / virology
  • Humans
  • Iran / epidemiology
  • Kinetics
  • Male
  • Middle Aged
  • RNA, Viral / urine
  • Saliva* / virology

Substances

  • RNA, Viral