Quality of life of patients after kidney transplant: ADHERE Brazil multicenter cross-sectional study

Aline R F Almeida; Fabiane R S Grincenkov; Fernando A B Colugnati; José O Medina-Pestana; Sabina De Geest; Helady Sanders-Pinheiro; ADHERE Brazil Study Team. Electronic address: aderebrasil.coordenacao@gmail.com

doi:10.1016/j.apnr.2024.151815

Quality of life of patients after kidney transplant: ADHERE Brazil multicenter cross-sectional study

Appl Nurs Res. 2024 Aug:78:151815. doi: 10.1016/j.apnr.2024.151815. Epub 2024 Jun 28.

Authors

Aline R F Almeida¹, Fabiane R S Grincenkov², Fernando A B Colugnati³, José O Medina-Pestana⁴, Sabina De Geest⁵, Helady Sanders-Pinheiro⁶; ADHERE Brazil Study Team. Electronic address: [email protected]

Affiliations

¹ Renal Transplantation Unit, University Hospital, Federal University of Juiz de Fora, Avenida Eugênio do Nascimento, S/N, Dom Bosco, Juiz de Fora, MG CEP: 36038-330, Brazil; Interdisciplinary Center for Studies and Research in Nephrology (NIEPEN), Faculty of Medicine, Federal University of Juiz de Fora. Avenida Eugênio do Nascimento, S/N, Dom Bosco, Juiz de Fora, MG CEP: 36038-330, Brazil. Electronic address: [email protected].
² Faculty of Psychology, Federal University of Juiz de Fora, Rua José Lourenço Kelmer, S/N, São Pedro, Juiz de Fora, MG CEP: 36036-900, Brazil. Electronic address: [email protected].
³ Renal Transplantation Unit, University Hospital, Federal University of Juiz de Fora, Avenida Eugênio do Nascimento, S/N, Dom Bosco, Juiz de Fora, MG CEP: 36038-330, Brazil; Interdisciplinary Center for Studies and Research in Nephrology (NIEPEN), Faculty of Medicine, Federal University of Juiz de Fora. Avenida Eugênio do Nascimento, S/N, Dom Bosco, Juiz de Fora, MG CEP: 36038-330, Brazil. Electronic address: [email protected].
⁴ Hospital do Rim e Hipertensão, Oswaldo Ramos Foundation, Nephrology Discipline, Federal University of São Paulo, Rua Borges Lagoa, 960, Vila Clementino, São Paulo, SP CEP: 04038-002, Brazil. Electronic address: [email protected].
⁵ Institute of Nursing Science, Department Public Health, University of Basel, Peterspl. 1, 4001 Basel, Switzerland; Academic Centre for Nursing and Midwifery, Department of Public Health and Primary Care, KU Leuven, Oude Markt 13, 3000 Leuven, Belgium. Electronic address: [email protected].
⁶ Renal Transplantation Unit, University Hospital, Federal University of Juiz de Fora, Avenida Eugênio do Nascimento, S/N, Dom Bosco, Juiz de Fora, MG CEP: 36038-330, Brazil; Interdisciplinary Center for Studies and Research in Nephrology (NIEPEN), Faculty of Medicine, Federal University of Juiz de Fora. Avenida Eugênio do Nascimento, S/N, Dom Bosco, Juiz de Fora, MG CEP: 36038-330, Brazil. Electronic address: [email protected].

PMID: 39053995
DOI: 10.1016/j.apnr.2024.151815

Abstract

Background: Quality of life (QoL) is a measure to evaluate kidney transplant (KT) results.

Aim: To describe the QoL profile in a larger sample of Brazilian patients who underwent KT according to age, sex, and access to KT.

Methods: We conducted a secondary data analysis of the ADHERE BRAZIL multicenter cross-sectional study including 1105 patients from 20 centers, considering KT access region and transplant activity. QoL was assessed by the WHOQOL-BREF. Data was compared using Generalized Estimating Equations.

Results: Overall, 58.5 % of the patients were men, mean age of 47.6 ± 12.6 years. The general QoL score was 81 ± 15.1, 58.6 ± 11.6 for physical, 65.5 ± 11.4 for psychological, 68.3 ± 17.1 for social relationships, and 64.2 ± 13.3 for environmental domain. Higher QoL scores were observed in men compared to women in three WHOQOL-BREF domains: psychological (OR:2.62; CI, 1.29 ̶ 3.95, p < 0.0001), social relationships (OR:3.21; CI, 1.2 ̶ 5.23, p = 0.002) and environmental (OR:3.79; CI:2.23 ̶ 5.35, p < 0.0001). Younger patients (18-44 years) had higher scores in the psychological (OR:-2.69; CI, -4.13 ̶ -1.25; p < 0.001; OR:-3.52; CI, -5.39 ̶ -1.66; p < 0.001) and social (OR:-3.46; CI, -5.64 ̶ -1.27; p = 0.002; OR:-7.17; CI, -10 ̶ -4.35; p < 0.0001) domains than older ones (45-59 and > 60 years, respectively). Patients from higher KT access region had higher scores in environmental domain (OR:3.53; CI, 0.28 ̶ 6.78; p = 0.033).

Conclusions: Featuring the results of KT under patient view, the physical and social relationships domains were the most and least affected, respectively. Lower QoL subgroups (females and age > 45 years) should be targeted in future multi-professional interventions.

Keywords: Chronic kidney failure, renal replacement therapy; Kidney transplantation; Multicenter study; Quality of life.

Publication types

Multicenter Study
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Brazil
Cross-Sectional Studies
Female
Humans
Kidney Transplantation* / psychology
Male
Middle Aged
Quality of Life* / psychology
Surveys and Questionnaires
Young Adult