An outbreak of botulism on a pig farm due to the newly described Clostridium botulinum type C

Caroline Le Maréchal; Martine Denis; Louis Vanlemmens; Léa Jambou; Gauthier Delvallez; Typhaine Poezevara; Mouna Abed-Zahar; Laure Diancourt; Marie-Agnès Baudouard; Eric Eveno; Marie-Hélène Bayon-Auboyer; Mustapha Fellag; Sandra Rouxel; Nadia Amenna; Christelle Mazuet; Jean-Marc Guéguen; Nicolas Rose

doi:10.1016/j.anaerobe.2024.102885

An outbreak of botulism on a pig farm due to the newly described Clostridium botulinum type C

Anaerobe. 2024 Oct:89:102885. doi: 10.1016/j.anaerobe.2024.102885. Epub 2024 Jul 24.

Authors

Caroline Le Maréchal¹, Martine Denis², Louis Vanlemmens³, Léa Jambou², Gauthier Delvallez⁴, Typhaine Poezevara², Mouna Abed-Zahar⁵, Laure Diancourt⁴, Marie-Agnès Baudouard⁵, Eric Eveno⁶, Marie-Hélène Bayon-Auboyer⁵, Mustapha Fellag⁵, Sandra Rouxel², Nadia Amenna⁵, Christelle Mazuet⁴, Jean-Marc Guéguen³, Nicolas Rose⁶

Affiliations

¹ ANSES, Ploufragan-Plouzané-Niort Laboratory, Hygiene and Quality of Poultry and Pig Products Unit, 22440, Ploufragan, France. Electronic address: [email protected].
² ANSES, Ploufragan-Plouzané-Niort Laboratory, Hygiene and Quality of Poultry and Pig Products Unit, 22440, Ploufragan, France.
³ SELAS de DELIAVET, Le Chemin Chaussée, 22440, La Bouillie, France.
⁴ Institut Pasteur, Université Paris Cité, CNR Bactéries Anaérobies et Botulisme, 75015, Paris, France.
⁵ LABOCEA, 7 Rue Du Sabot, 22440, Ploufragan, France.
⁶ ANSES, Ploufragan-Plouzané-Niort Laboratory, Epidemiology, Health and Welfare Unit, 22440, Ploufragan, France.

PMID: 39059624
DOI: 10.1016/j.anaerobe.2024.102885

Abstract

This study reports a botulism outbreak on a pig farm. Clostridium botulinum type C was detected using PCR. The gene encoding the toxin corresponds to a novel type C neurotoxin recently described in a human botulism outbreak, raising the question of its prevalence in pigs and the related risks to humans.

Keywords: Botulism; Clostridium botulinum type C; Outbreak; Pig.

MeSH terms

Animals
Botulinum Toxins / genetics
Botulism* / epidemiology
Botulism* / microbiology
Botulism* / veterinary
Clostridium botulinum / classification
Clostridium botulinum / genetics
Clostridium botulinum / isolation & purification
Clostridium botulinum type C* / classification
Clostridium botulinum type C* / genetics
Clostridium botulinum type C* / isolation & purification
Disease Outbreaks*
Farms*
Polymerase Chain Reaction
Swine
Swine Diseases* / epidemiology
Swine Diseases* / microbiology

Substances

Botulinum Toxins