Direct RAS inhibitors turn 10

Nat Chem Biol. 2024 Oct;20(10):1238-1241. doi: 10.1038/s41589-024-01691-5.

Authors

Jonathan M L Ostrem¹, Ulf Peters², Kevan M Shokat^{3

4}

Affiliations

¹ Department of Medicine, University of California, San Francisco, San Francisco, CA, USA. [email protected].
² Kumquat Biosciences, San Diego, CA, USA.
³ Department of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.
⁴ Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.

PMID: 39060392
DOI: 10.1038/s41589-024-01691-5

No abstract available

Publication types

News

MeSH terms

Antineoplastic Agents / chemistry
Antineoplastic Agents / pharmacology
Enzyme Inhibitors / chemistry
Enzyme Inhibitors / pharmacology
Humans
ras Proteins* / antagonists & inhibitors
ras Proteins* / metabolism

Substances

ras Proteins
Enzyme Inhibitors
Antineoplastic Agents