Visual Outcomes in Ectopia Lentis in Marfan Syndrome: A Study of Four Surgical Techniques in Children and Adults

Medicina (Kaunas). 2024 Jul 5;60(7):1098. doi: 10.3390/medicina60071098.

Abstract

Background/Objectives: To evaluate how the surgical technique and type of implanted intraocular lens influence the postoperative visual acuity and complications in ectopia lentis associated to Marfan syndrome patients. Materials and Methods: The medical records and videos of ectopia lentis surgeries in patients (children and adults) with Marfan syndrome, were retrospectively reviewed and compared. The study included 33 eyes that underwent four different intraocular lens implantation (IOL) techniques: IOL in conjunction with a simple capsular tension ring, IOL in conjunction with a Cionni modified capsular tension ring (m-CTR), two-point scleral IOL fixation and IOL with one haptic in the bag and one haptic sutured to the sclera. Results: Vision significantly improved from a mean preoperative visual acuity of 0.1122 to a mean postoperative visual acuity of 0.4539 in both age groups (p < 0.0001), with no difference in the primary outcome between children and adults. The most common surgical technique used in both age groups was IOL in conjunction with an m-CTR. There was only one major postoperative complication requiring additional surgery. Conclusions: Zonular weakness mainly influenced by age was the most important selection criterion for the surgical approach. Regardless of the technique employed, the postoperative visual acuity was improved in both adults and children.

Keywords: Marfan syndrome; ectopia lentis surgical techniques; modified Cionni capsular tension rings.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Ectopia Lentis* / etiology
  • Ectopia Lentis* / surgery
  • Female
  • Humans
  • Lens Implantation, Intraocular* / adverse effects
  • Lens Implantation, Intraocular* / methods
  • Male
  • Marfan Syndrome* / complications
  • Marfan Syndrome* / physiopathology
  • Marfan Syndrome* / surgery
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome
  • Visual Acuity*
  • Young Adult

Grants and funding

This research received no external funding.