Determining the 1-hour post-load glucose which identifies diabetes in Africans: Insight from the Africans in America study

Diabetes Res Clin Pract. 2024 Aug:214:111792. doi: 10.1016/j.diabres.2024.111792. Epub 2024 Jul 26.

Abstract

Diagnosing diabetes by shortening the OGTT to 1-h and substituting 1-h post-load glucose (PG) ≥ 209 mg/dL for 2-h PG≥200 mg/dL has been proposed. One-hour PG≥209 mg/dL is from a meta-analysis without any African-descent populations. Our data suggest 1-h PG≥183 mg/dL maybe more optimal for Africans. As with waist circumference guidelines, population-specific thresholds may be appropriate.

Keywords: Diabetes Screening; Oral Glucose Tolerance Test; Type 2 Diabetes.

MeSH terms

  • Adult
  • African People
  • Black People
  • Blood Glucose* / analysis
  • Diabetes Mellitus / blood
  • Diabetes Mellitus / diagnosis
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / diagnosis
  • Diabetes Mellitus, Type 2 / epidemiology
  • Female
  • Glucose Tolerance Test*
  • Humans
  • Male
  • Middle Aged
  • United States / epidemiology

Substances

  • Blood Glucose