Bilateral Chorea-Ballism Associated With Non-ketotic Hyperglycemia: A Case Report

Cureus. 2024 Jun 26;16(6):e63221. doi: 10.7759/cureus.63221. eCollection 2024 Jun.

Abstract

The intricate workings of uncontrolled diabetes and its effects on the nervous system are not fully understood. However, it is known that this condition can lead to various neurological manifestations, including altered consciousness and epileptic seizures. In this case study, a 66-year-old woman presented with abnormal ballistic movements and chorea due to severe hyperglycemia. The results of her brain MRI suggested diabetic striatopathy. Fortunately, her symptoms improved significantly with the normalization of blood glucose levels and appropriate medical intervention. While the exact pathophysiology remains elusive, there is speculation that dysfunction of dopaminergic activity may play a role. The management of these complications involves stabilizing blood glucose levels and providing symptomatic relief. Despite the limited understanding of the underlying mechanisms, these neurological complications generally have a positive prognosis.

Keywords: caudate and lenticular nuclei; chorea-ballism; diabetes mellitus; magnetic resonance imaging; non-ketotic hyperglycemia.

Publication types

  • Case Reports