Prognosis of major trauma in patients older than 85 years admitted to the ICU, a registry-based study

Eur J Trauma Emerg Surg. 2024 Dec;50(6):3199-3208. doi: 10.1007/s00068-024-02622-8. Epub 2024 Jul 30.

Abstract

Background: The aging population in France and Western Europe is on the rise, particularly among individuals aged 65 years and older. Although older adults are susceptible to traumatic injuries, they constitute a minority of trauma center admissions especially those aged 85 and above. The aim of our study was to investigate the prognostic factors for mortality among the older old population (aged 85 years and above) managed in ICU of Traumabase group trauma centers.

Methods: This retrospective observational cohort study, conducted from 2013 to 2022, analyzed all severely injured older patients (aged ≥ 85 years) managed in 14 ICU trauma centers enrolled in the Traumabase registry. The study examined sociodemographic, clinical, and outcome variables. Frailty was assessed using the Clinical Frailty Scale.

Results: Among the 365 older trauma patients, 190 (52.1%) were classified as non-frail (CFS 1-3), 80 (21.9%) as pre-frail (CFS 4,5), and 95 (26%) as frail (CFS 6-9). Falls were the most common mechanism of injury. High mortality rates were observed, with 43.5% ICU mortality and 45.5% mortality at day 30. Factors most associated with ICU mortality included traumatic brain injury (CGS < 13), pre-hospital micromethod hemoglobin < 13 and severity of injury (ISS > 16).

Conclusion: Factors such as traumatic brain injury and severe hemorrhage (micromethod hemoglobin < 13) and ISS > 16 are associated with ICU mortality in in patients older than 85 years trauma patient. Early geriatric intervention is crucial for optimizing outcomes in this vulnerable population.

Keywords: Clinical frailty scale; Elderly patients; Frailty; Mortality; Trauma.

Publication types

  • Observational Study
  • Multicenter Study

MeSH terms

  • Aged, 80 and over
  • Female
  • Frail Elderly / statistics & numerical data
  • Frailty / epidemiology
  • Frailty / mortality
  • France / epidemiology
  • Hospital Mortality
  • Humans
  • Injury Severity Score*
  • Intensive Care Units* / statistics & numerical data
  • Male
  • Prognosis
  • Registries*
  • Retrospective Studies
  • Risk Factors
  • Trauma Centers*
  • Wounds and Injuries* / mortality