Enhancing naloxone

Sci Signal. 2024 Jul 30;17(847):eadr9944. doi: 10.1126/scisignal.adr9944. Epub 2024 Jul 30.

Abstract

A negative allosteric modulator of the μ-opioid receptor enhances the efficacy of naloxone.

MeSH terms

  • Allosteric Regulation
  • Animals
  • Humans
  • Naloxone*
  • Narcotic Antagonists*
  • Receptors, Opioid, mu* / metabolism

Substances

  • Naloxone
  • Receptors, Opioid, mu
  • Narcotic Antagonists