Research progress of malignant peritoneal mesothelioma with paraneoplastic syndrome: A review

J Surg Oncol. 2024 Sep;130(3):533-542. doi: 10.1002/jso.27737. Epub 2024 Jul 31.

Abstract

Malignant peritoneal mesothelioma (MPM) is a rare and invasive tumor, and some patients will develop paraneoplastic syndrome (PS) during the course of the disease. This review summarizes PS associated with MPM, focusing on the clinical characteristics and treatment progress in hematological, endocrine, rheumatic, neurological, urinary, and other systems to decrease missed diagnosis and misdiagnosis, help early diagnosis and prompt treatment, and provide guidance for the clinical decision-making of this kind of patients.

Keywords: hypoglycemia; malignant peritoneal mesothelioma; neoplastic fever; nephrotic syndrome; paraneoplastic syndrome; thrombocytosis.

Publication types

  • Review

MeSH terms

  • Humans
  • Lung Neoplasms / complications
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / pathology
  • Lung Neoplasms / therapy
  • Mesothelioma* / complications
  • Mesothelioma* / diagnosis
  • Mesothelioma* / pathology
  • Mesothelioma* / therapy
  • Mesothelioma, Malignant* / diagnosis
  • Mesothelioma, Malignant* / pathology
  • Mesothelioma, Malignant* / therapy
  • Paraneoplastic Syndromes* / diagnosis
  • Paraneoplastic Syndromes* / etiology
  • Peritoneal Neoplasms* / complications
  • Peritoneal Neoplasms* / diagnosis
  • Peritoneal Neoplasms* / pathology
  • Peritoneal Neoplasms* / therapy