Review of whole-body magnetic resonance imaging in multiple myeloma

Jpn J Radiol. 2024 Dec;42(12):1381-1391. doi: 10.1007/s11604-024-01635-y. Epub 2024 Aug 1.

Abstract

Multiple Myeloma (MM) is a hematological malignancy affecting bone marrow, most frequently in elderly men. Imaging has a crucial role in this disease. Recently, whole-body MRI has been introduced and it has gained growing interest due to is high sensitivity and specificity in evaluating bone marrow involvement in MM. Diffusion-weighted sequences (DWI) with apparent diffusion coefficient (ADC) maps have emerged as the most sensitive technique to evaluate patients with MM, both in the pre- and post-treatment setting. Aim of this review is to provide an overview of the role and main imaging findings of whole-body MRI in MM.

Keywords: Diffusion weighted imaging; Multiple Myeloma; Oncologic imaging; Whole-body magnetic resonance imaging.

Publication types

  • Review

MeSH terms

  • Bone Marrow / diagnostic imaging
  • Bone Marrow / pathology
  • Diffusion Magnetic Resonance Imaging / methods
  • Humans
  • Magnetic Resonance Imaging* / methods
  • Multiple Myeloma* / diagnostic imaging
  • Sensitivity and Specificity
  • Whole Body Imaging* / methods