Chronic ulcer in a patient with essential thrombocythemia taking hydroxyurea

Dermatol Online J. 2024 Jun 15;30(3). doi: 10.5070/D330363872.

Abstract

Chronic skin ulcers in patients with suspected pyoderma gangrenosum can, on closer inspection and further workup, have a different cause. Recognition of key features on clinical examination such as the presence of atrophie blanche is key to avoid misdiagnosis of pyoderma gangrenosum and its subsequent treatment with high-dose corticosteroids and other immunosuppressive medications.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Chronic Disease
  • Female
  • Humans
  • Hydroxyurea* / adverse effects
  • Hydroxyurea* / therapeutic use
  • Leg Ulcer
  • Pyoderma Gangrenosum* / chemically induced
  • Pyoderma Gangrenosum* / diagnosis
  • Pyoderma Gangrenosum* / drug therapy
  • Pyoderma Gangrenosum* / pathology
  • Skin Ulcer / chemically induced
  • Skin Ulcer / pathology
  • Thrombocythemia, Essential* / complications
  • Thrombocythemia, Essential* / drug therapy

Substances

  • Hydroxyurea