Sustainable synthesis of fluorescent polymer carbon dots@PVA for sensitive chlortetracycline detection

Luminescence. 2024 Aug;39(8):e4846. doi: 10.1002/bio.4846.

Abstract

Antibiotic residues persist in the environment and represent serious health hazards; thus, it is important to develop sensitive and effective detection techniques. This paper presents a bio-inspired way to make water-soluble fluorescent polymer carbon dots (PCDs@PVA) by heating biomass precursors and polyvinyl alcohol (PVA) together. For example, the synthesized PCDs@PVA are very stable with enhanced emission intensity. This property was observed in a wide range of environmental conditions, including those with changing temperatures, pH levels, UV light, and ionic strength. PCDs@PVA detected the antibiotic chlortetracycline (CTCs) with great selectivity against structurally related compounds and a low detection limit of 20 nM, demonstrating outstanding sensitivity and specificity. We confirmed the sensor's practical application through real sample analysis, yielding recovery rates of 98%-99% in samples of milk, honey, and river water. The synthesized PCDs@PVA fluorescence sensor was successfully used for CTCs detection in real samples.

Keywords: PCDs@PVA; chlortetracycline; fluorescence sensing; inner filter effect; real sample analysis.

MeSH terms

  • Animals
  • Anti-Bacterial Agents / analysis
  • Anti-Bacterial Agents / chemical synthesis
  • Anti-Bacterial Agents / chemistry
  • Carbon* / chemistry
  • Chlortetracycline* / analysis
  • Fluorescent Dyes* / chemical synthesis
  • Fluorescent Dyes* / chemistry
  • Honey / analysis
  • Hydrogen-Ion Concentration
  • Limit of Detection
  • Milk / chemistry
  • Polymers / chemical synthesis
  • Polymers / chemistry
  • Polyvinyl Alcohol* / chemistry
  • Quantum Dots* / chemistry
  • Rivers / chemistry
  • Spectrometry, Fluorescence
  • Water Pollutants, Chemical / analysis

Substances

  • Chlortetracycline
  • Polyvinyl Alcohol
  • Carbon
  • Fluorescent Dyes
  • Anti-Bacterial Agents
  • Polymers
  • Water Pollutants, Chemical