Pediatric abscessed craniopharyngioma: A case report and review of literature

Neurochirurgie. 2024 Sep;70(5):101584. doi: 10.1016/j.neuchi.2024.101584. Epub 2024 Jul 31.

Abstract

Background: Craniopharyngiomas are rare sellar and suprasellar tumors affecting children and adults. The spontaneous abscessation of this lesion is an extremely rare occurrence with a total of 10 cases reported in the literature including 2 cases in the pediatric population.

Observation: We report a case of abscessed craniopharyngioma in a 10-year-old girl, revealed by intracranial hypertension and diabetes insipidus with a double component (solid and cystic) lesion of the sella visualized on cerebral MRI. The patient underwent surgical decompression via endoscopic endonasal transsphenoidal approach coupled with antibiotic treatment with an uneventful postoperative course and improvement of her symptoms.

Conclusion: Abscessed craniopharyngiomas are rare and challenging entities. We highlight through our case and literature review the importance of an in-depth patient's history as well as a clinical-radiological correlation in allowing for a positive preoperative diagnosis even in patients with no meningeal or infection signs.

Keywords: Abscessed craniopharyngioma; Craniopharyngioma; Secondary pituitary abscess; Sellar abscess.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Brain Abscess / surgery
  • Child
  • Craniopharyngioma* / surgery
  • Diabetes Insipidus / etiology
  • Female
  • Humans
  • Intracranial Hypertension / etiology
  • Intracranial Hypertension / surgery
  • Magnetic Resonance Imaging
  • Pituitary Neoplasms* / surgery