Modern insulin treatment for type 2 diabetes

Ugeskr Laeger. 2024 Jul 8;186(28):V03240172. doi: 10.61409/V03240172.
[Article in Danish]

Abstract

This review summarises the current and possible future insulin treatment of type 2 diabetes. The type 2 diabetes treatment guidelines prioritise a person-centred approach with various options before insulin addressing cardiorenal protection. Long-acting daily insulin injections are warranted in severe hyperglycaemia or when glycaemic targets are not met. Insulin, when possible, should be combined with other agents to lower insulin dosage, weight gain and hypoglycaemia. Once-weekly insulin offers a promising treatment, reducing injection burden, enhancing treatment satisfaction, and lowering the risk of severe hypoglycaemia, potentially improving type 2 diabetes management.

Publication types

  • Review
  • English Abstract

MeSH terms

  • Diabetes Mellitus, Type 2* / drug therapy
  • Drug Administration Schedule
  • Humans
  • Hypoglycemia / chemically induced
  • Hypoglycemia / prevention & control
  • Hypoglycemic Agents* / administration & dosage
  • Hypoglycemic Agents* / therapeutic use
  • Insulin* / administration & dosage
  • Insulin* / therapeutic use

Substances

  • Hypoglycemic Agents
  • Insulin