Storage, preservation, and rehabilitation of living heart valves to treat congenital heart disease

Med. 2024 Aug 9;5(8):859-862. doi: 10.1016/j.medj.2024.07.004.

Abstract

Heart valve disease patients undergo multiple surgeries to replace structurally degraded valve prostheses, highlighting the need for valve replacements with growth and self-repair capacity. Given allogeneic valve transplantation's promise in meeting these goals by delivering a living valve replacement, we propose a framework for preserving and rehabilitating living valves ex vivo.

MeSH terms

  • Heart Defects, Congenital* / rehabilitation
  • Heart Defects, Congenital* / surgery
  • Heart Valve Diseases / rehabilitation
  • Heart Valve Diseases / surgery
  • Heart Valve Prosthesis Implantation / methods
  • Heart Valve Prosthesis*
  • Heart Valves / surgery
  • Humans