A Chicken-and-Egg Predicament: Malignant Hypertension Versus HIV-Induced Thrombotic Microangiopathic Anemia Conundrum

Cureus. 2024 Jul 11;16(7):e64304. doi: 10.7759/cureus.64304. eCollection 2024 Jul.

Abstract

Thrombotic microangiopathy (TMA) is a condition characterized by hemolytic anemia, thrombocytopenia, and organ damage due to the formation of microthrombi. It can be classified as primary or secondary, with secondary TMA being associated with conditions such as infections, autoimmune diseases, and malignancies. This report details the case of a 39-year-old male with secondary TMA, exploring the potential roles of malignant hypertension and HIV infection with the aim of examining the potential link between malignant hypertension and HIV infection in the development of TMA, highlighting the need for a thorough and broad diagnostic approach.

Keywords: end-stage renal failure; endothelial damage; human immunodeficiency virus (hiv)-positive; severe hypertension; thrombotic microangiopathy (tma).

Publication types

  • Case Reports