Hemophagocytic Lymphohistiocytosis Induced by Brucellosis: A Case Report

Cureus. 2024 Jul 10;16(7):e64287. doi: 10.7759/cureus.64287. eCollection 2024 Jul.

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a hyper-inflammatory condition triggered by infections, malignancies, or autoimmune conditions. Brucellosis is a zoonotic disease contracted through exposure to infected animals or consumption of unpasteurized dairy products. The complications of both pathologies may be fatal. This report presents a rare instance of HLH induced by Brucellosis, highlighting the need for increased recognition of this life-threatening association.

Keywords: brucella melitensis; hemophagocytic lymphohistiocytosis (hlh); hlh-94; human brucellosis; hyper-inflammatory syndrome.

Publication types

  • Case Reports