Mapping ethical, legal, and social implications (ELSI) of fertility preservation

J Assist Reprod Genet. 2024 Sep;41(9):2495-2514. doi: 10.1007/s10815-024-03210-w. Epub 2024 Aug 14.

Abstract

Research question: The study examines the ethical, legal, and social implications of fertility preservation, highlighting its importance across oncofertility, elective egg freezing, and posthumous assisted reproduction, as well as its impact on transgender individuals undergoing gender-affirming surgeries.

Design: A comprehensive analysis of 600 articles, focusing on a diverse range of disciplines, including bioethics, psychology, and sociology, to explore public and healthcare professionals' knowledge, patient experiences, and regulatory constraints.

Results: The body of literature is growing, indicating increasing recognition of FP's significance. Key themes included the centrality of counseling and informed decision-making, especially in oncofertility and EEF, and ethical debates surrounding informed consent and the autonomy of involved individuals. The analysis underscored a western-centric bias in current research, emphasizing the need for more inclusive and culturally sensitive studies.

Conclusions: The study calls for a nuanced understanding of FP, advocating for policies that consider ethical, cultural, and social dimensions. It suggests the necessity for interdisciplinary research to address identified gaps, particularly in understanding non-Western perspectives and ensuring equitable access to FP services globally. Moreover, the review emphasizes the importance of integrating patient-centric approaches and ethical frameworks to guide FP practices and policies, ensuring they respect diverse values and meet individuals' needs.

Keywords: Ethical; Fertility preservation; Gaps in research; Geographic distribution of research; Legal and Social Implications (ELSI); Mapping.

Publication types

  • Review

MeSH terms

  • Counseling / ethics
  • Cryopreservation / ethics
  • Decision Making / ethics
  • Female
  • Fertility Preservation* / ethics
  • Humans
  • Informed Consent / ethics
  • Male
  • Reproductive Techniques, Assisted / ethics
  • Reproductive Techniques, Assisted / legislation & jurisprudence
  • Transgender Persons